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Asacolon® 1000mg Suppositories
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What is Ulcerative Proctitis?
You have been prescribed suppositories to help treat ulcerative proctitis. Ulcerative proctitis is caused by inflammation in your bottom (rectum).
Asacolon 1000mg suppositories contain mesalazine, a medicine that can reduce inflammation and also help to relieve your symptoms.
Asacolon 1000mg Suppositories
How to use suppositories
It is important to use suppositories regularly and consistently as prescribed.
You should use Asacolon 1000mg suppositories for as long as your doctor has advised, even if you feel better.
This will make sure the inflammation has gone down.
Try and have a poo before using your suppository
Wash your hands and undress from the waist down
Peel back the wrapper to remove the suppository and hold the blunt end
Lie on your side with your top leg bent towards your stomach
Relax, spread your buttocks and insert the suppository into your bottom, tip end first
Push it in as far as you can (at least an inch)
Squeeze your legs and buttocks together to help the suppository stay in
Watch this short video for instructions on how to use your mesalazine suppositories.
- You might find it easier to use the suppository before bed
- You can lubricate the tip of the suppository with water or a water-based lubricant to make it easier to insert
- If the suppository comes out within 10 minutes of inserting it, don’t worry, try again with another suppository
- Try not to do a poo for an hour after inserting the suppository to give it time to work
- You may experience leakage during the night. Don’t worry, this is normal because the suppository starts to melt once it is inserted. You can put a towel down on your bed to absorb any leaks
If you have any questions or concerns about your Asacolon suppositories, please speak to your healthcare professional
Frequently Asked Questions
What are Asacolon 1000mg suppositories?
Asacolon 1000mg suppositories contain the active ingredient mesalazine, which is an
anti-inflammatory medicine used to treat ulcerative proctitis. Asacolon 1000mg suppositories act locally to reduce and prevent inflammation in the rectum.
Can I use Asacolon 1000mg suppositories if I am pregnant, breast-feeding or planning to have a baby?
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using Asacolon 1000mg suppositories.
Can I drive and/or operate machinery when I am using Asacolon 1g suppositories?
Asacolon 1000mg suppositories are not expected to affect your ability to drive or operate machinery.
How should I use Asacolon 1000mg suppositories?
You should use Asacolon 1000mg suppositories as your doctor/nurse has told you.
Check with your healthcare provider if you are not sure.
Asacolon 1000mg suppositories should only be used rectally, which means they have to be inserted through the anus (bottom). Do not take by mouth.
How often should I use Asacolon 1000mg suppositories?
You should use Asacolon 1000mg suppositories exactly as your doctor/nurse has told you. Check with your healthcare provider if you are not sure.
The recommended dose is one Asacolon 1000mg suppository, once a day, at bedtime.
The dose should be adjusted by your doctor as per your condition.
What should I do if I use more Asacolon 1000mg suppositories than I am supposed to?
Contact a doctor if you are in doubt, so they can decide what to do.
If you use too many Asacolon 1000mg suppositories on one occasion, just take your next dose as prescribed. Do not use a smaller amount.
What should I do if I forget to use Asacolon 1000mg suppositories?
If you forget to use your Asacolon suppository, use one as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed. Then use the next dose at its usual time.
You must not use a double dose to make up for a forgotten dose.
Can I stop using Asacolon 1000mg suppositories?
Do not stop using Asacolon 1000mg suppositories without talking to your doctor first.
If you have any further questions on the use of Asacolon 1000mg suppositories, ask your doctor, nurse or pharmacist.
What should I do if I get a side effect?
Reporting of side effects: If you get any side effects, talk to you doctor, pharmacist or nurse. This includes any possible effects not listed in the package leaflet.
You can also report side effects directly via https://www.hpra.ie/report-an-issue/medicines-for-human-use/side-effects.
You can also report side effects to the marketing authorisation holder. Tillotts Pharma Ltd. On +353 1 2942015 or Pvireland@tillotts.com
How should I store Asacolon 1000mg suppositories?
Keep Asacolon 1000mg suppositories out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the blister strip
and on the carton. The expiry date refers to the last day of that month.
Do not store above 30°C. Do not refrigerate or freeze.
Keep your suppositories in the original container to protect them from light.
What do Asacolon 1000mg suppositories look like?
Asacolon 1000mg suppositories are light beige coloured, torpedo-shaped suppositories.
Are Asacolon 1000mg suppositories suitable for vegetarians or vegans?
The active substance in Asacolon 1000mg suppositories is mesalazine and the other ingredient is hard fat. The hard fat is from a non-animal origin.
Therefore, Asacolon 1000mg suppositories are suitable for vegetarians and vegans.
References
1. Andus T et al. Inflamm Bowel Dis 2010; 16(11): 1947–1956.
2. Data on file, Tillotts Pharma UK Limited. [Nurse suppository top tips – December 2020].
Report a side effect
Reporting of side effects: If you get any side effects, talk to you doctor, pharmacist or nurse. This includes any possible effects not listed in the package leaflet.
You can also report side effects directly via https://www.hpra.ie/report-an-issue/medicines-for-human-use/side-effects.
You can also report side effects to the marketing authorisation holder. Tillotts Pharma Ltd. On +353 1 2942015 or Pvireland@tillotts.com.
By reporting side effects, you can help provide more information on the safety of this medicine.
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NP-ASACLN1000-IE-00001 | March 2026
